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Variable (N (%))
|
Q1
|
Q2
|
Q3
|
Q4
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P value
|
|---|
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2.16–3.78 %
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3.86–4.95 %
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4.96–6.37 %
|
6.39–13.2 %
|
|---|
|
(n = 31)
|
(n = 30)
|
(n = 31)
|
(n = 30)
|
|---|
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Demographics
| | | | | |
|
Age (years), mean ± SD
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57.03 ± 14.01
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62.47 ± 12.47
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62.06 ± 9.71
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63.97 ± 9.42
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0.11
|
|
Male
|
17 (54.8 %)
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20 (66.7 %)
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23 (74.2 %)
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22 (73.3 %)
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0.34
|
|
Black
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3 (9.7 %)
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3 (10.0 %)
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4 (12.9 %)
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1 (3.3 %)
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0.61
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|
Blood pressure (mmHg), mean ± SD
| | | | | |
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Systolic
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123.63 ± 23.04
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123.96 ± 25.00
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136.52 ± 23.97
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127.17 ± 18.05
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0.10
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|
Diastolic
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72.03 ± 13.63
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68.11 ± 12.87
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71.71 ± 13.87
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68.69 ± 12.93
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0.57
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Medical history
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Acute coronary syndrome on presentation
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8 (25.8 %)
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10 (33.3 %)
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15 (48.4 %)
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10 (33.3 %)
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0.30
|
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Prior myocardial infarction
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4 (12.9 %)
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10 (33.3 %)
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8 (25.8 %)
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14 (46.7 %)
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0.03
|
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Hypertension
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20 (64.5 %)
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27 (90.0 %)
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25 (80.6 %)
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23 (76.7 %)
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0.11
|
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Diabetes
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6 (19.4 %)
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8 (26.7 %)
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16 (51.6 %)
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16 (53.3 %)
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0.01
|
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Chronic dialysis
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2 (6.5 %)
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2 (6.7 %)
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3 (9.7 %)
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1 (3.3 %)
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0.80
|
|
Congestive heart failure
|
7 (22.6 %)
|
11 (36.7 %)
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8 (25.8 %)
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6 (20.0 %)
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0.47
|
|
Chronic obstructive lung disease
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2 (6.5 %)
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3 (10.0 %)
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2 (6.5 %)
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1 (3.3 %)
|
0.78
|
|
Peripheral vascular disease
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0 (0.0 %)
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2 (6.7 %)
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4 (12.9 %)
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4 (13.3 %)
|
0.19
|
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Hyperlipidemia
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18 (58.1 %)
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24 (80.0 %)
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26 (83.9 %)
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23 (76.7 %)
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0.09
|
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Angiographic findings
| | | | | |
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Number of diseased vessels, median [QR]
|
0.0 [0.0, 0.0]
|
0.0 [0.0, 1.0]
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1.0 [1.0, 2.0]
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2.0 [2.0, 3.0]
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<0.001
|
|
Multi-vessel coronary disease
|
0 (0.0 %)
|
1 (3.3 %)
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9 (29.0 %)
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24 (80.0 %)
|
<0.001
|
|
Gensini score, median [IQR]
|
19.5 [18.5, 21.0]
|
21.8 [18.5, 27.0]
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29.0 [25.5, 44.5]
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45.8 [32.5, 65.0]
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<0.001
|
|
Labs, mean ± SD
| | | | | |
|
Ejection fraction (%), median [IQR]
|
60.00 [43.75, 63.63]
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60.00 [45.00, 65.00]
|
53.00 [35.00, 65.00]
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55.00 [47.00, 60.00]
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0.46
|
|
Hemoglobin, (g/dL)
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13.55 ± 1.57
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13.30 ± 1.23
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13.54 ± 1.66
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12.28 ± 2.48
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0.02
|
|
White blood count (1000/mm3), median [IQR]
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7.72 [6.00, 8.55]
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7.22 [6.40, 8.60]
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7.95 [5.60, 9.34]
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8.26 [6.60, 9.14]
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0.14
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|
LDL cholesterol (mg/dL)
|
101.55 ± 31.19
|
76.48 ± 30.45
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90.04 ± 43.00
|
81.46 ± 34.67
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0.11
|
|
Serum creatinine (mg/dL), median [IQR]
|
1.01 [0.81, 1.30]
|
1.02 [0.90, 1.22]
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1.13 [0.90, 1.41]
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1.08 [0.85, 1.24]
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0.55
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Estimated glomerular filtration rate, (mL/min)
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69.01 ± 28.21
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70.29 ± 30.70
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64.18 ± 33.68
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69.96 ± 29.88
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0.85
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- Baseline characteristics of the study population according to percent area stenosis
-
SD standard deviation, IQR inter-quartile range, Hg mercury, min minute
